Welcome to the FightNeglectedDiseases@Home project. Our aim is to find novel drugs and targets for infectious diseases.

Whole genome DNA sequencing offers unprecedented knowledge about pathogens, but converting this knowledge into novel therapeutic drugs remains a challenge.

The scientific literature is a treasure trove of potentially useful drugs. However, choosing the right one to test in clinical trials is difficult, especially if one does not know the protein target that it inhibits.

To 'jump-start' drug discovery we are attempting to use computers to dock each potential drug into 3-dimensional models of all proteins in the pathogen proteome.

These calculations require vast computational resources. We therefore reply on the generous donation of computer time from volunteers all over the world who are connected to our project through BOINC.

Thus far we have completed the malaria calculations, and are continuing with a similar search for novel drugs/targets against TB. If you would like to get involved, please go to our BOINC server here.